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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MTDH
All Species:
26.36
Human Site:
S239
Identified Species:
72.5
UniProt:
Q86UE4
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86UE4
NP_848927.2
582
63837
S239
T
E
Q
L
T
T
A
S
F
P
V
G
S
K
K
Chimpanzee
Pan troglodytes
XP_001147163
582
63892
S239
T
E
Q
L
T
T
A
S
F
P
V
G
S
K
K
Rhesus Macaque
Macaca mulatta
XP_001092477
582
63836
S239
T
E
Q
L
T
T
A
S
F
P
V
G
S
K
K
Dog
Lupus familis
XP_854970
649
70607
S306
T
E
Q
L
T
T
A
S
F
P
V
G
S
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q80WJ7
579
63827
S238
T
E
Q
L
T
T
A
S
F
P
V
G
S
K
K
Rat
Rattus norvegicus
Q9Z1W6
581
63951
S238
T
E
Q
L
T
T
A
S
F
P
V
G
S
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_418351
533
58224
P195
A
L
S
P
T
S
Y
P
G
D
T
L
L
N
V
Frog
Xenopus laevis
NP_001086463
562
62020
S224
E
Q
F
T
S
G
S
S
H
S
A
G
T
R
K
Zebra Danio
Brachydanio rerio
XP_001923099
525
56785
T187
N
L
A
G
T
W
E
T
K
V
S
N
R
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
98.6
80.2
N.A.
91
90.3
N.A.
N.A.
45.3
45.8
33.8
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
99.1
83.6
N.A.
94.5
94.1
N.A.
N.A.
60.3
60.8
50.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
6.6
20
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
13.3
53.3
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
0
12
0
0
0
67
0
0
0
12
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% D
% Glu:
12
67
0
0
0
0
12
0
0
0
0
0
0
12
0
% E
% Phe:
0
0
12
0
0
0
0
0
67
0
0
0
0
0
0
% F
% Gly:
0
0
0
12
0
12
0
0
12
0
0
78
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
12
0
0
0
0
67
89
% K
% Leu:
0
23
0
67
0
0
0
0
0
0
0
12
12
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
0
0
0
0
0
0
0
12
0
12
0
% N
% Pro:
0
0
0
12
0
0
0
12
0
67
0
0
0
0
0
% P
% Gln:
0
12
67
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
12
12
0
% R
% Ser:
0
0
12
0
12
12
12
78
0
12
12
0
67
0
0
% S
% Thr:
67
0
0
12
89
67
0
12
0
0
12
0
12
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
12
67
0
0
0
12
% V
% Trp:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _